Zhu Liuluan

Zhu Liuluan

Professor

Doctoral Supervisor (Capital Medical University)

Master’s Supervisor (Capital Medical University, Peking University Health Science Center)

Academic Appointments:

2024.04–Present: Chair, Youth Working Group on Infectious Diseases, Beijing Research Association for Chronic Disease Control and Health Education

2023.09–Present: Member, Expert Pool for Transformation of Medical and Health Science & Technology Achievements, Beijing

2023.07–Present: Member, Beijing International Medical Promotion Association

2022.12–Present: Member, Infection Specialty Committee, Beijing Association of the Integrating of Traditional and Western Medicine

2016.04–Present: Standing Committee Member, Translational Medicine Committee, Orthopedics Branch, China Research and Promotion of Traditional Chinese Medicine

Reviewer for projects of the National Natural Science Foundation of China (NSFC), the United States–Israel Binational Science Foundation (BSF), and others

Academic Journal Appointments:

Editorial Board Member, Microbes & Immunity

Guest Editor, Frontiers in Cell and Developmental Biology

Independent Reviewer for Journal of Nanobiotechnology, Journal of Infectious Diseases, Journal of Cellular Physiology, Immunology & Cell Biology, Autoimmunity, Chinese Journal of Tissue Engineering Research, and other academic journals

Research Focus:

Regulation of Infection and Innate Immunity

Education and Work Experience:

Sep. 2001 – Jul. 2005, College of Life Sciences, Northeast Normal University, Biotechnology (Honors Program), B.Sc. in Science

Sep. 2005 – Jul. 2010, Peking Union Medical College / Tsinghua University School of Medicine, Biochemistry and Molecular Biology, Ph.D. in Science, Advisor: Prof. Fang Fude

Aug. 2010 – Nov. 2011, Institute for Infectious Diseases, Beijing Ditan Hospital Affiliated to Capital Medical University, Research Intern

Nov. 2011 – Nov. 2015, Institute for Infectious Diseases, Beijing Ditan Hospital Affiliated to Capital Medical University, Assistant Researcher

Dec. 2014 – Aug. 2015, Penn State University Hershey Medical Center, Visiting Scholar

Nov. 2015 – Nov. 2020, Institute for Infectious Diseases, Beijing Ditan Hospital Affiliated to Capital Medical University, Associate Researcher

Nov. 2020 – Present, Institute for Infectious Diseases, Beijing Ditan Hospital Affiliated to Capital Medical University, Researcher

Selected Publications:

1. Wenjuan Peng#, Qiushi Qin#, Rui Li#, Yujia Liu#, Lan Li, Yue Zhang, Liuluan Zhu*(corresponding author). Blimp-1 Orchestrates Macrophage Polarization and Metabolic Homeostasis via Purine Biosynthesis in Sepsis. Cell Death & Disease. 2025 Feb 06;16(1):72 doi:10.1038/s41419-025-07405-6 (IF: 8.1 Q1, CAS Zone 1)

2. Ming Han#, Yujia Liu#, Ying Cao#, Yue Zhang, Yonghong Yan, Shuwei Deng, Xiaoxue Yuan, Huichun Xing, Yuan Huang* and Liuluan Zhu*(corresponding author). The imbalance of NET homeostasis is associated with portal vein thrombosis in patients with decompensated cirrhosis. Journal of Clinical and Translational Hepatology. doi: 10.14218/JCTH.2024.00165 (IF: 3.6 Q2)

3. Yanxi Zhou#, Shuwei Deng#, Chunjing Du, Liang Zhang, Lan Li, Yujia Liu, Yijie Wang, Yue Zhang*, Liuluan Zhu*(corresponding author). Leukotriene B4-induced neutrophil extracellular traps impede the clearance of Pneumocystis. European J Immunol. 2024 Feb. Doi: 10.1002/eji.202350779. (IF: 5.4 Q2)

4. Yue Zhang#, Lan Li#, Yuanni Liu#, Wei Zhang#, Wenjuan Peng, Shuai Zhang, Renliang Qu, Yuan Ma, Zishuai Liu, Ziruo Ge, Yanxi Zhou, Wen Tian, Yi Shen, Li Liu, Jianping Duan, Zhihai Chen*, Liuluan Zhu*(corresponding author). Identification of CCL20 as a Prognostic Predictor for Severe Fever With Thrombocytopenia Syndrome Based on Plasma Proteomics. J Infect Dis. 2024 Jan 25:jiae039. Doi: 10.1093/infdis/jiae039. (IF: 6.4 Q1)

5. Beibei Wang#, Liuluan Zhu#(co-first author), Bei Jia#, Chenchen Zhao#, Ju Zhang#, Fangyuan Li, Jiarui Li, Nan Ding, Can Zhang, Yu Hao, Shuai Tong, Jiajia Wang, Guoli Li, Yang Fan, Henghui Zhang, Rui Li, Juan Du, Yaxian Kong, Yue Zhang, Xiaoyu Yang, Junyan Han, Zhengya Yu, Zhongtao Du, Hong Zheng, Christian Kosan, Ang Li, Chen Chen, Yaluan Ma*, Hui Zeng*. Sepsis induces non-classic innate immune memory in granulocytes. Cell Rep, 2023 Aug 28;42(9):113044. Doi: 10.1016/j.celrep.2023.113044. (IF: 8.8, Q1, CAS Zone 1)

6. Qiushi Qin#, Rui Li#, Lan Li, Yue Zhang, Shuwei Deng, Liuluan Zhu*(corresponding author). Multi-target regulation of pro-inflammatory cytokine production by transcription factor Blimp-1. Inflamm Res. 2023 Feb;72(2):217-220. doi:10.1007/s00011-022-01671-2 (IF: 6.7 Q2)

7. Ying Cao#, Weili Mai#, Rui Li#, Shuwei Deng, Lan Li, Yanxi Zhou, Qiushi Qin, Yue Zhang, Xingang Zhou, Ming Han, Pu Liang, Yonghong Yan, Yu Hao, Wen Xie, Jie Yan, Liuluan Zhu *(corresponding author). Macrophages evoke autophagy of hepatic stellate cells to promote liver fibrosis in NAFLD mice via the PGE2/EP4 pathway. Cell Mol Life Sci. 2022 May 19;79(6):303. Doi:10.1007/s00018-022-04319-w (IF: 8.0 Q1)

8. Yue Zhang#, Kai Han#, Chunjing Du#, Rui Li, Jingyuan Liu, Hui Zeng*, Liuluan Zhu* (co-corresponding author), Ang Li*. Carboxypeptidase B blocks ex vivo activation of the anaphylatoxin-neutrophil extracellular trap axis in neutrophils from COVID-19 patients. Critical Care. 2021 Feb 8;25(1):51. Doi:10.1186/s13054-021-03482-z (IF:15.1, Q1, CAS Zone 1)

9. Yue Zhang#, Rui Song#, Yi Shen#, Yongxiang Zhao, Zhenghua Zhao, Tianli Fan, Xiaoyu Yang, Lin Wang, Wei Zhang, Chong Chen, Di Tian, Ying Wang, Jing Wen, Ziruo Ge, Xiaoli Yu, Li Liu, Yang Feng, Jianping Duan, Yanli Ma, Xingwang Li, Hui Zeng, Zhihai Chen*, Liuluan Zhu* (corresponding author). High levels of circulating cell-free DNA are associated with a poor prognosis in patients with severe fever with thrombocytopenia syndrome. Clin Infect Dis. 2020 Apr 15;70(9):1941-1949. Doi: 10.1093/cid/ciz553. (IF: 11.8 Q1, CAS Zone 1)

Awards and Honors:

Outstanding Young Talent, “Phoenix Program” of Chaoyang District, Sep. 2023

“Basic and Clinical Research on the Progression and Reversal of Chronic Liver Diseases,”
Second Prize, Capital Medical University Natural Science Award, 2023, University Level, 7th Contributor

“Establishment and Application of Innovative Traditional Chinese Medicine Techniques to Improve the Efficacy of Severe Liver Disease Treatment,” First Prize, Science and Technology Award of the Chinese Association of Traditional Chinese Medicine, 2021, 11th Contributor

“Immunopathological Mechanisms and Early Clinical Warning of Severe Outcomes in Emerging Infectious Diseases,” Third Prize, 1st Capital Medical University Natural Science Award, 2020, University Level, 1st Contributor

“Establishment and Application of the Detoxification, Cooling Blood, and Strengthening Spleen Method to Improve the Efficacy of Acute-on-Chronic Liver Failure Treatment,”
Second Prize, Huaxia Medical Science and Technology Award, 2018, Provincial-Ministerial Level, 9th Contributor

Contact Information:

Email: zhuliuluan@ccmu.edu.cn

Work Phone: 13581658271