张淑妍

研究员

首医青年博导

硕士生导师（北京大学医学部） 

研究方向：

脂滴生物学及脂代谢 

教育及工作经历：

教育经历

2000/09–2004/07，北京工商大学，生物工程专业，学士

2004/09–2009/07，中国科学院研究生院，生物化学与分子生物学专业，博士 

工作经历

2009/08-2022/07, 中国科学院生物物理研究所，助理、副研究员

2022/08-2023/10，球盟会qmh网页版登录/北京市感染性疾病研究中心，副研究员

2023/11-至今，球盟会qmh网页版登录/北京市感染性疾病研究中心，研究员

代表性论文：

1. Zhang S#,*, Zhang M#, Xu S#, Fu X, Liao Q, Pan B, Cui L, Liu P*. Preparation of fatty acid solutions for investigating lipid signaling, metabolism, and lipid droplets. Protein & Cell, 2024; pwae068. (in press) （影响因子：13.6）(Impact Factor: 13.6)

2. Zhang K#, Zhou C#, Li Z#, Li X#, Zhou Z, Cheng L, Mirza AH, Shi Y, Chen B, Zhang M, Cui L, Zhang C, Wei T, Zhang X*, Zhang S*, Liu P*. Identification of lipid droplets in gut bacteria. Protein & Cell. 2023;14:143–148. （影响因子：13.6）(Impact Factor: 13.6)

3. Bingbing Chen#, Yumeng Shi#, Kai Zhang, Yanzhong Chang, Pengcheng Fu*, Pingsheng Liu*, Shuyan Zhang*. Inulin Reduces Liver Triacylglycerol by Increasing Lipid Droplet Lipolysis in Fat-loaded Mice. Food Research International. 2023;112226. （影响因子：8.1）(Impact Factor: 8.1)

4. Quan Yuan#, Kaixuan Zheng#, Ting Huang, Zelun Zhi, Yilu Xu, Liujuan Cui, Pingsheng Liu*, Shuyan Zhang*. One amino acid drives the lipid droplet targeting sequence of a new noncoding RNA-encoded protein to mitochondrion. PROTEOMICS. 2023, 2200301. （影响因子：3.4）(Impact Factor: 3.4)

5. Huang T#, Bamigbade AT#, Xu S#, Deng Y, Xie K, Ogunsade OO, Mirza AH, Wang J, Liu P*, Zhang S*. Identification of noncoding RNA-encoded proteins on lipid droplets. Science Bulletin. 2021;66(4):314-318. （影响因子：20.577）(Impact Factor: 20.577)

6. Mirza AH#, Cui L#, Zhang S*, Liu P*. Comparative proteomics reveals that lipid droplet-anchored mitochondria are more sensitive to cold in brown adipocytes. BBA Mol Cell Biol Lipids. 2021;1866(10):158992. （影响因子：5.228）(Impact Factor: 5.228)

7. Deng Y#, Zhou C#, Mirza AH, Bamigbade AT, Zhang S*, Xu S*, Liu P*. Rab18 binds PLIN2 and ACSL3 to mediate lipid droplet dynamics. BBA Molecular and Cell Biology of Lipids. 2021:158923. （影响因子：5.228）(Impact Factor: 5.228)

8. Liu Q, Zhou Z, Liu P*, Zhang S*. Comparative proteomic study of liver lipid droplets and mitochondria in mice housed at different temperatures. FEBS Lett. 2019;593(16):2118-2138. （影响因子：3.057）(Impact Factor: 3.057)

9. Zhang S#, Wang Y#, Cui L, Deng Y, Xu S, Yu J, Cichello S, Serrero G, Ying Y, Liu P*. Morphologically and Functionally Distinct Lipid Droplet Subpopulations. Sci Rep. 2016;6:29539. （影响因子：4.122）(Impact Factor: 4.122)

10. Ding Y#, Zhang S#, Yang L, Na H, Zhang P, Zhang H, Wang Y, Chen Y, Yu J, Huo C, Xu S, Garaiova M, Cong Y, Liu P*. Isolating lipid droplets from multiple species. Nat Protoc. 2013;8(1):43-51. （影响因子：9.646）(Impact Factor: 9.646) 

获奖情况：

2023年度“首医青年学者”

联系方式：

电子邮箱：syzhang@ibp.ac.cn

工作电话：010-84322620